Case 32 of 40
New confusion after surgery may appear before fever or circulatory deterioration
Example case for staff education
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Read the case transcript
Page 1
Panel 1: Before surgery
Colin normally manages daily life independently.
Asha: He keeps track of all our arrangements.
Panel 2: Postoperative day 1
The first postoperative day is mentally clear.
Colin: I remember what the surgeon explained.
Panel 3: Day 3 morning
New inattention appears before a fever is recorded.
Asha: He cannot follow what we are talking about.
Panel 4: Day 3 morning
The new cognitive change prompts clinical assessment.
Nurse Tom: This is different from yesterday. Please assess him now.
Panel 5: Day 3 morning
The team looks for postoperative causes.
Ward doctor Amira: Check pain, medicines, oxygenation and possible surgical complications.
Panel 6: Day 3 afternoon
Fever and circulatory deterioration follow.
Nurse Tom: His observations have changed since the earlier assessment.
Panel 7: Day 3
Investigation identifies an anastomotic leak.
Ward doctor Amira: He needs urgent treatment for this complication.
Panel 8: Day 3
Source control, antibiotics and supportive treatment begin.
Nurse Tom: We will keep explaining what is happening as he wakes.
Panel 9: Day 6
Physiological improvement does not end the delirium.
Colin: Why am I in a different room?
Page 2
Panel 10: Day 8
Attention still varies despite satisfactory surgical progress.
Asha: Sometimes he sounds clear, then loses the thread again.
Panel 11: Day 8
Pain relief and medication effects are reassessed.
Ward doctor Amira: He needs comfort without avoidable drowsiness.
Panel 12: Day 10
Poor intake requires practical assistance and nutritional review.
Nurse Tom: I will help you get started and see how much you manage.
Panel 13: Day 12
Rehabilitation proceeds during continuing delirium.
Physiotherapist Lin: We can work in short sessions when he can engage.
Panel 14: Week 3
He needs more help than the healed wound suggests.
Ward doctor Amira: The discharge plan must include his cognitive and daily care needs.
Panel 15: Week 4
Fewer prompts are needed, but fatigue remains.
Colin: I do better before I get tired.
Panel 16: Week 6
The episode is explained as his attention improves.
Colin: I remember very little of those days.
Panel 17: Week 8
He is improving but remains less independent than before.
Asha: We have help while he builds up again.
Panel 18: Week 8
Fear of another episode becomes part of planning.
Colin: If I need surgery again, I want us to plan for this.
Sources
- [S38] Marcantonio, E.R. (2012) ‘Postoperative delirium: a 76-year-old woman with delirium following surgery’, JAMA, 308(1), pp. 73–81.
- [S04] Nair, A., Arfan, S., Holder, S.S., Bacchus, K.I. and Stear, T.J. (2023) ‘Persistent Postoperative Delirium Following Laparoscopic Cholecystectomy’, Cureus, 15(6), e40523.
- [P43] Dharmarajan K, Swami S, Gou RY, Jones RN, Inouye SK. Pathway from Delirium to Death: Potential In-Hospital Mediators of Excess Mortality. Journal of the American Geriatrics Society. 2017;65:1026–1033.
- [G01] National Institute for Health and Care Excellence. Delirium: prevention, diagnosis and management in hospital and long-term care. CG103.


Commentary
Colin first deteriorates in his ability to follow familiar conversation. The nurse and Asha notice the change before obvious fever or circulatory instability develops. Staff begin a focused surgical assessment at that point rather than waiting for marked changes in physical observations.
A postoperative complication is later found and treated. The example uses only the procedural detail needed to explain the case. The relevant source describes confusion appearing before obvious sepsis [S38]. After treatment, Colin’s breathing and circulation stabilise, but attention, sleep and daily activities remain affected.
Staff review medicines and pain relief, help with nutrition and adapt movement to what Colin can manage [P43, G01]. These measures respond to his needs; the case does not promise that they will shorten delirium by a particular number of days. Rehabilitation continues while cognitive symptoms remain.
Asha describes Colin’s usual abilities and changes through each day. Her observations add to examination and help staff avoid mistaking one clear conversation for recovery. At eight weeks, Colin is home with extra help and is worried about future surgery. Discuss plans for any later procedure without suggesting that delirium will inevitably recur or that prevention can guarantee it will not. Marcantonio’s reported patient later had an operation without delirium, but the contribution of individual preventive measures was not established [S38].