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Case 37 of 40

Investigate new neurological signs even when infection may explain delirium

Example case for staff education

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Case 37 comic, page 1: The history that changes the assessment. Pneumonia and kidney injury accompany acute confusion. Treatment of the systemic illness begins promptly. His gait had changed before the fever began. A focal finding does not fit a simple systemic explanation. A minor fall several weeks earlier is recalled. The team confirms treatment relevant to bleeding risk. CT identifies a subdural collection with pressure on the brain. The teams coordinate treatment and anticoagulant management. Treatment proceeds while the systemic illness is also managed.
Case 37 · Page 1 of 2 · Open full-size illustration
Case 37 comic, page 2: After treatment of the collection. Arousal and weakness improve after treatment. Attention remains impaired despite those gains. Residual delirium prompts continued assessment and care. Nutrition, sleep and comfort remain active concerns. Rehabilitation follows current neurological and cognitive abilities. Further neurological follow-up and medication plans are explained. Cognition improves gradually rather than immediately. He remains less independent than before the illness. Both the structural illness and delirium course are reviewed.
Case 37 · Page 2 of 2 · Open full-size illustration

Commentary

Walter has pneumonia and kidney injury, which may both contribute to delirium. Neither adequately explains his worsening walking before the infection or the new difference between the two sides on examination. He takes an anticoagulant. Information from his relative also reveals a minor fall several weeks earlier. These findings prompt urgent brain imaging while his other illnesses are treated.

The scan finds a subdural haematoma. Pneumonia is also present, and both conditions may contribute to delirium. Arrange urgent neurosurgical assessment while continuing medical treatment. The relevant teams manage anticoagulation according to the intracranial bleeding and planned intervention. The comic gives no general instruction for reversing anticoagulation.

Erdogan and colleagues reported a patient with several possible causes and a clinically important subdural collection [S07]. This teaching example includes both structural brain disease and illness elsewhere in the body, but uses a different history and course. Temple’s report supports reassessment when neurological findings change, even after one explanation has been found [S31].

After drainage, Walter becomes more alert and his weakness improves. Attention and daily activities recover more slowly. Identify which findings required imaging and how information from relatives changed the assessment. Continue delirium care and rehabilitation even after a procedure has improved some symptoms.

Read the case transcript

Page 1

Panel 1: Day 1

Pneumonia and kidney injury accompany acute confusion.

Priya: He became much sleepier over the last two days.

Panel 2: Day 1

Treatment of the systemic illness begins promptly.

Ward doctor Amira: We also need to examine his neurological state.

Panel 3: Day 1

His gait had changed before the fever began.

Priya: He was less steady for a couple of weeks.

Panel 4: Day 1

A focal finding does not fit a simple systemic explanation.

Ward doctor Amira: We need urgent brain imaging.

Panel 5: Day 1

A minor fall several weeks earlier is recalled.

Priya: He fell, but did not think he had been badly hurt.

Panel 6: Day 1

The team confirms treatment relevant to bleeding risk.

Pharmacist Samir: We have checked the medicine and the last dose.

Panel 7: Day 1

CT identifies a subdural collection with pressure on the brain.

Ward doctor Amira: This needs urgent neurosurgical assessment as well as treatment of the pneumonia.

Panel 8: Day 1

The teams coordinate treatment and anticoagulant management.

Neurosurgeon Leon: We will discuss the procedure and address the bleeding risk.

Panel 9: Day 2

Treatment proceeds while the systemic illness is also managed.

Nurse Tom: We are checking both neurological and general medical changes.

Page 2

Panel 10: Day 3

Arousal and weakness improve after treatment.

Walter: I can move that arm more easily.

Panel 11: Day 3

Attention remains impaired despite those gains.

Priya: He still cannot follow the whole discussion.

Panel 12: Day 4

Residual delirium prompts continued assessment and care.

Ward doctor Amira: We should not assume the operation resolved every problem.

Panel 13: Day 5

Nutrition, sleep and comfort remain active concerns.

Nurse Tom: I will stay while you get started.

Panel 14: Day 7

Rehabilitation follows current neurological and cognitive abilities.

Physiotherapist Lin: Take your time. We can practise this again later.

Panel 15: Week 2

Further neurological follow-up and medication plans are explained.

Ward doctor Amira: The plan needs to be clear to everyone continuing his care.

Panel 16: Week 3

Cognition improves gradually rather than immediately.

Walter: I still forget what comes next sometimes.

Panel 17: Week 5

He remains less independent than before the illness.

Priya: We have arranged help while he continues recovering.

Panel 18: Week 6

Both the structural illness and delirium course are reviewed.

Ward doctor Amira: Let us compare what he can do now with before admission.

Sources